4Mg Semaglutide Vails Nova

What is semaglutide?

Semaglutide is used for weight loss, to lower blood sugar levels in type 2 diabetes, and to reduce the risk of major cardiovascular events and chronic kidney disease in certain adult patients. 

Semaglutide is a GLP-1 agonist that works by reducing appetite, delaying gastric emptying, increasing insulin release, and lowering the amount of glucagon released. 

Semaglutide brand names are Ozempic, Rybelus, and Wegovy , which are made by Novo Nordisk, and are FDA-approved for different conditions. Semaglutide FDA approval was first granted on December 5, 2017, for the brand Ozempic.

What is semaglutide used for?

Wegovy (semaglutide) for weight loss 

• Wegovy (semaglutide) is used for weight loss and weight maintenance in patients 12 years and older with obesity

• Used for reducing major cardiovascular event risks (such as heart attack, stroke, or death) in adults with type 2 diabetes with known heart disease

• Injection is given 1 time a week under the skin of the stomach (belly), the thigh, or the upper arm, using an autoinjector (pen)
• This injection should be used in addition to a reduced-calorie diet and increased physical activity

Semaglutide injection

• Semaglutide is used to treat type 2 diabetes in adults to help control blood sugar levels used together with diet and exercise,
• Used for reducing major cardiovascular event risks (such as heart attack, stroke, or death) in adults with type 2 diabetes with known heart disease
• Used to reduce the risk of kidney function decline, kidney failure, and death due to cardiovascular disease, in adults with chronic kidney disease (CKD) and type 2 diabetes
• Injection is given 1 time a week under the skin of the stomach (belly), the thigh, or the upper arm, using an autoinjector (pen).

How does semaglutide work?

Semaglutide's mechanism of action involves mimicking a natural hormone in the body called GLP-1 which:

• Stimulates insulin production from the pancreas
• Reduces liver sugar production
• Slows down digestion
• Helps control appetite and food intake.

GLP-1 is a naturally occurring hormone that is released when we eat, to help us regulate our food intake. Semaglutide works by activating GLP-1 receptors, this lowers appetite, slows how quickly the stomach empties, and increases insulin production, so you feel fuller for longer and eat less, which leads to weight loss, control of blood sugar levels, and reduces the risk of cardiovascular disease. 

The way semaglutide works for kidney-related risk reduction is not fully understood.

Semaglutide belongs to the drug class called GLP-1 receptor agonists. 

Semaglutide side effects

Common semaglutide side effects

Common semaglutide side effects may include low blood sugar (in people with type 2 diabetes), upset stomach, heartburn, burping, gas, bloating, nausea, vomiting, stomach pain, loss of appetite, diarrhea, constipation, stomach flu symptoms, headache, dizziness, tiredness.

Stomach or gastrointestinal side effects are common, but they tend to be mild and clear up in a few weeks and usually will not interfere with long-term treatment. Stomach side effects can be more common with higher doses.

Tips for managing stomach side effects

Following these tips may help you manage stomach semaglutide side effects:

• Eat more slowly
• Eat smaller meals
• Chose more bland, low-fat foods (like crackers, toast, and rice)
• Avoid eating greasy, fried foods or sugar treats
• Eat foods that contain water (like soup or gelatin)
• Do not t lie down right after eating
• Drink clear or ice-cold liquids
• If possible, go outside for fresh air if you feel sick to your stomach
• Ryebelsus is not recommended in patients with severe gastroparesis.